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Analysis of mRNA recognition by human thymidylate synthase
Expression of hTS (human thymidylate synthase), a key enzyme in thymidine biosynthesis, is regulated on the translational level through a feedback mechanism that is rarely found in eukaryotes. At low substrate concentrations, the ligand-free enzyme binds to its own mRNA and stabilizes a hairpin stru...
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| Veröffentlicht in: | Biosci Rep |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Portland Press Ltd.
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4274661/ https://ncbi.nlm.nih.gov/pubmed/25423174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20140137 |
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