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PQ-69, a novel and selective adenosine A(1) receptor antagonist with inverse agonist activity
Potent and selective adenosine A(1) receptor (A(1)AR) antagonists with favourable pharmacokinetic properties used as novel diuretics and antihypertensives are desirable. Thus, we designed and synthesized a series of novel 4-alkylamino substitution-2-arylpyrazolo[4,3-c]quinolin-3-one derivatives. The...
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Publicat a: | Purinergic Signal |
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Autors principals: | , , , , , , , , |
Format: | Artigo |
Idioma: | Inglês |
Publicat: |
Springer Netherlands
2014
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4272367/ https://ncbi.nlm.nih.gov/pubmed/25248972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-014-9424-5 |
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