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PQ-69, a novel and selective adenosine A(1) receptor antagonist with inverse agonist activity

Potent and selective adenosine A(1) receptor (A(1)AR) antagonists with favourable pharmacokinetic properties used as novel diuretics and antihypertensives are desirable. Thus, we designed and synthesized a series of novel 4-alkylamino substitution-2-arylpyrazolo[4,3-c]quinolin-3-one derivatives. The...

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Detalhes bibliográficos
Publicado no:Purinergic Signal
Main Authors: Lu, Min, Wang, Bo, Zhang, Cheng, Zhuang, Xiaomei, Yuan, Mei, Wang, Haoshan, Li, Weizhang, Su, Ruibin, Li, Jin
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4272367/
https://ncbi.nlm.nih.gov/pubmed/25248972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-014-9424-5
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