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Rolofylline, an adenosine A(1) receptor antagonist, inhibits osteoclast differentiation as an inverse agonist

BACKGROUND AND PURPOSE: Adenosine may be generated by hydrolysis of extracellular nucleotides by ectonucleotidases, including ectonucleoside triphosphate diphosphohydrolase 1 (CD39), ecto-5′-nucleotidase (CD73), nucleotide pyrophosphatase phosphodiesterase 1 (NPP-1) and tissue non-specific alkaline...

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Detalhes bibliográficos
Main Authors: He, Wenjie, Wilder, Tuere, Cronstein, Bruce N
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838692/
https://ncbi.nlm.nih.gov/pubmed/23962057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12342
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