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Some implications of receptor theory for in vivo assessment of agonists, antagonists and inverse agonists
Drug effects can be classified into three major phenotypes: agonist, antagonist and inverse agonist. Agonist and inverse agonist effects are associated with receptor activation and inactivation, respectively, whereas antagonism implies that a drug produces no effect when administered alone but block...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1866283/ https://ncbi.nlm.nih.gov/pubmed/16460689 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2005.12.038 |
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