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Radiolabeled somatostatin receptor antagonists are preferable to agonists for in vivo peptide receptor targeting of tumors

Targeting neuroendocrine tumors expressing somatostatin receptor subtypes (sst) with radiolabeled somatostatin agonists is an established diagnostic and therapeutic approach in oncology. While agonists readily internalize into tumor cells, permitting accumulation of radioactivity, radiolabeled antag...

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Detalhes bibliográficos
Main Authors: Ginj, Mihaela, Zhang, Hanwen, Waser, Beatrice, Cescato, Renzo, Wild, Damian, Wang, Xuejuan, Erchegyi, Judit, Rivier, Jean, Mäcke, Helmut R., Reubi, Jean Claude
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618814/
https://ncbi.nlm.nih.gov/pubmed/17056720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607761103
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