Radiolabeled somatostatin receptor antagonists are preferable to agonists for in vivo peptide receptor targeting of tumors

Targeting neuroendocrine tumors expressing somatostatin receptor subtypes (sst) with radiolabeled somatostatin agonists is an established diagnostic and therapeutic approach in oncology. While agonists readily internalize into tumor cells, permitting accumulation of radioactivity, radiolabeled antag...

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Bibliografiske detaljer
Main Authors: Ginj, Mihaela, Zhang, Hanwen, Waser, Beatrice, Cescato, Renzo, Wild, Damian, Wang, Xuejuan, Erchegyi, Judit, Rivier, Jean, Mäcke, Helmut R., Reubi, Jean Claude
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2006
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618814/
https://ncbi.nlm.nih.gov/pubmed/17056720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607761103
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