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Radiolabeled somatostatin receptor antagonists are preferable to agonists for in vivo peptide receptor targeting of tumors

Targeting neuroendocrine tumors expressing somatostatin receptor subtypes (sst) with radiolabeled somatostatin agonists is an established diagnostic and therapeutic approach in oncology. While agonists readily internalize into tumor cells, permitting accumulation of radioactivity, radiolabeled antag...

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Main Authors: Ginj, Mihaela, Zhang, Hanwen, Waser, Beatrice, Cescato, Renzo, Wild, Damian, Wang, Xuejuan, Erchegyi, Judit, Rivier, Jean, Mäcke, Helmut R., Reubi, Jean Claude
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2006
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618814/
https://ncbi.nlm.nih.gov/pubmed/17056720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607761103
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