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Design and in vitro Characterization of Highly Sst(2)-selective Somatostatin Antagonists Suitable for Radio-Targeting
Radiolabeled sst(2) and sst(3) antagonists are better candidates for tumor targeting than agonists with comparable binding characteristics.1 Because the majority of neuroendocrine tumors express sst(2), we used the known antagonists Acetyl-pNO(2)Phe(2)-c[dCys(3)-Tyr(7)-dTrp(8)-Lys(9)-Thr(10)-Cys(14)...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2789649/ https://ncbi.nlm.nih.gov/pubmed/18543899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm701618q |
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