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Switch from Antagonist to Agonist after Addition of a DOTA Chelator to a Somatostatin Analog

PURPOSE: Peptide receptor targeting has become an increasingly attractive method to target tumors diagnostically and radiotherapeutically. Peptides linked to a variety of chelators have been developed for this purpose. They have, however rarely been tested for their agonistic or antagonistic propert...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Reubi, Jean Claude, Erchegy, Judit, Cescato, Renzo, Waser, Beatrice, Rivier, Jean E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025705/
https://ncbi.nlm.nih.gov/pubmed/20396884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-010-1445-x
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