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Agonist-Biased Signaling at the sst2A Receptor: The Multi-Somatostatin Analogs KE108 and SOM230 Activate and Antagonize Distinct Signaling Pathways

Somatostatin analogs that activate the somatostatin subtype 2A (sst2A) receptor are used to treat neuroendocrine cancers because they inhibit tumor secretion and growth. Recently, new analogs capable of activating multiple somatostatin receptor subtypes have been developed to increase tumor responsi...

詳細記述

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書誌詳細
主要な著者: Cescato, Renzo, Loesch, Kimberly A., Waser, Beatrice, Mäcke, Helmut R., Rivier, Jean E., Reubi, Jean Claude, Schonbrunn, Agnes
フォーマット: Artigo
言語:Inglês
出版事項: The Endocrine Society 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802896/
https://ncbi.nlm.nih.gov/pubmed/19910453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2009-0321
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