Pentoxifylline Attenuates Nitrogen Mustard-induced Acute Lung Injury, Oxidative Stress and Inflammation

Nitrogen mustard (NM) is a toxic alkylating agent that causes damage to the respiratory tract. Evidence suggests that macrophages and inflammatory mediators including tumor necrosis factor (TNF)α contribute to pulmonary injury. Pentoxifylline is a TNFα inhibitor known to suppress inflammation. In th...

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Publicado no:Exp Mol Pathol
Main Authors: Sunil, Vasanthi R., Vayas, Kinal N., Cervelli, Jessica A., Malaviya, Rama, Hall, LeRoy, Massa, Christopher B., Gow, Andrew J., Laskin, Jeffrey D., Laskin, Debra L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4271840/
https://ncbi.nlm.nih.gov/pubmed/24886962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexmp.2014.05.009
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