Protective role of spleen-derived macrophages in lung inflammation, injury, and fibrosis induced by nitrogen mustard

Nitrogen mustard (NM) is a vesicant that causes lung injury and fibrosis, accompanied by a persistent macrophage inflammatory response. In these studies we analyzed the spleen as a source of these cells. Splenectomized (SPX) and sham control rats were treated intratracheally with NM (0.125 mg/kg) or...

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Pubblicato in:Am J Physiol Lung Cell Mol Physiol
Autori principali: Venosa, Alessandro, Malaviya, Rama, Gow, Andrew J., Hall, Leroy, Laskin, Jeffrey D., Laskin, Debra L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2015
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4683320/
https://ncbi.nlm.nih.gov/pubmed/26475734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00276.2015
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