Attenuation of Acute Nitrogen Mustard-Induced Lung Injury, Inflammation and Fibrogenesis by a Nitric Oxide Synthase Inhibitor

Nitrogen mustard (NM) is a toxic vesicant known to cause damage to the respiratory tract. Injury is associated with increased expression of inducible nitric oxide synthase (iNOS). In these studies we analyzed the effects of transient inhibition of iNOS using aminoguanidine (AG) on NM-induced pulmona...

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Detalhes bibliográficos
Main Authors: Malaviya, Rama, Venosa, Alessandro, Hall, LeRoy, Gow, Andrew J., Sinko, Patrick J., Laskin, Jeffrey D., Laskin, Debra L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516137/
https://ncbi.nlm.nih.gov/pubmed/22981630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2012.08.027
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