Attenuation of Nitrogen Mustard-Induced Pulmonary Injury and Fibrosis by Anti-Tumor Necrosis Factor-α Antibody

Nitrogen mustard (NM) is a bifunctional alkylating agent that causes acute injury to the lung that progresses to fibrosis. This is accompanied by a prominent infiltration of macrophages into the lung and upregulation of proinflammatory/profibrotic cytokines including tumor necrosis factor (TNF)α. In...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Malaviya, Rama, Sunil, Vasanthi R., Venosa, Alessandro, Verissimo, Vivianne L., Cervelli, Jessica A., Vayas, Kinal N., Hall, LeRoy, Laskin, Jeffrey D., Laskin, Debra L.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Immunotherapy for Nitrogen Mustard Lung Damage
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4659692/
https://ncbi.nlm.nih.gov/pubmed/26243812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfv161
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