Protective Role of Surfactant Protein-D Against Lung Injury and Oxidative Stress Induced by Nitrogen Mustard

Nitrogen mustard (NM) is a vesicant known to cause acute pulmonary injury which progresses to fibrosis. Macrophages contribute to both of these pathologies. Surfactant protein (SP)-D is a pulmonary collectin that suppresses lung macrophage activity. Herein, we analyzed the effects of loss of SP-D on...

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Vydáno v:Toxicol Sci
Hlavní autoři: Sunil, Vasanthi R, Vayas, Kinal N, Cervelli, Jessica A, Ebramova, Elena V, Gow, Andrew J, Goedken, Michael, Malaviya, Rama, Laskin, Jeffrey D, Laskin, Debra L
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
Témata:
Protective Effects of Surfactant Protein-D to Nitrogen Mustard
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6204765/
https://ncbi.nlm.nih.gov/pubmed/30060251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfy188
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