Lung injury, oxidative stress and fibrosis in mice following exposure to nitrogen mustard

Nitrogen mustard (NM) is a cytotoxic vesicant known to cause acute lung injury which progresses to fibrosis. Herein, we developed a murine model of NM-induced pulmonary toxicity with the goal of assessing inflammatory mechanisms of injury. C57Bl6/J mice were euthanized 1–28 d following intratracheal...

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Veröffentlicht in:Toxicol Appl Pharmacol
Hauptverfasser: Sunil, Vasanthi R., Vayas, Kinal N., Abramova, Elena V., Rancourt, Raymond, Cervelli, Jessica A., Malaviya, Rama, Goedken, Michael, Venosa, Alessandro, Gow, Andrew J., Laskin, Jeffrey D., Laskin, Debra L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7066865/
https://ncbi.nlm.nih.gov/pubmed/31678244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2019.114798
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