Intrinsic disorder drives N-terminal ubiquitination by Ube2w

Ubiquitination of the αN-terminus of protein substrates has been reported sporadically over the past twenty years. However the identity of an enzyme responsible for this unique ubiquitin (Ub) modification has only recently been elucidated. We show the ubiquitin-conjugating enzyme (E2) Ube2w employs...

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Xehetasun bibliografikoak
Argitaratua izan da:Nat Chem Biol
Egile Nagusiak: Vittal, Vinayak, Shi, Lei, Wenzel, Dawn M., Scaglione, K. Matthew, Duncan, Emily D., Basrur, Venkatesha, Elenitoba-Johnson, Kojo S. J., Baker, David, Paulson, Henry L., Brzovic, Peter S., Klevit, Rachel E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4270946/
https://ncbi.nlm.nih.gov/pubmed/25436519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1700
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