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Biochemical and Structural Characterization of the Ubiquitin-Conjugating Enzyme UBE2W Reveals the Formation of a Noncovalent Homodimer

The biochemical and structural characterization of ubiquitin-conjugating enzymes (E2s) over the past 30 years has fostered important insights into ubiquitin transfer mechanisms. Although many of these enzymes share high sequence and structural conservation, their functional roles in the cell are dec...

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Main Authors: Vittal, Vinayak, Wenzel, Dawn M., Brzovic, Peter S., Klevit, Rachel E.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3758794/
https://ncbi.nlm.nih.gov/pubmed/23709311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12013-013-9633-5
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