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Mitosis, double strand break repair, and telomeres: A view from the end

Double strand break (DSB) repair is suppressed during mitosis because RNF8 and downstream DNA damage response (DDR) factors, including 53BP1, do not localize to mitotic chromatin. Discovery of the mitotic kinase-dependent mechanism that inhibits DSB repair during cell division was recently reported....

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Detaylı Bibliyografya
Yayımlandı:Bioessays
Yazar: Cesare, Anthony J
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: WILEY Periodicals, Inc. 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4270212/
https://ncbi.nlm.nih.gov/pubmed/25171524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201400104
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