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Mitosis, double strand break repair, and telomeres: A view from the end
Double strand break (DSB) repair is suppressed during mitosis because RNF8 and downstream DNA damage response (DDR) factors, including 53BP1, do not localize to mitotic chromatin. Discovery of the mitotic kinase-dependent mechanism that inhibits DSB repair during cell division was recently reported....
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| Опубликовано в: : | Bioessays |
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| Главный автор: | |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
WILEY Periodicals, Inc.
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4270212/ https://ncbi.nlm.nih.gov/pubmed/25171524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201400104 |
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