An epithelial circadian clock controls pulmonary inflammation and glucocorticoid action

The circadian system is as an important regulator of immune function. Human inflammatory lung diseases frequently show time-of-day variation in symptom severity and lung function, but the mechanisms and cell types that are underlying these effects remain unclear. We show that pulmonary antibacterial...

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Bibliographic Details
Published in:Nat Med
Main Authors: Gibbs, Julie, Ince, Louise, Matthews, Laura, Mei, Junjie, Bell, Thomas, Yang, Nan, Saer, Ben, Begley, Nicola, Poolman, Toryn, Pariollaud, Marie, Farrow, Stuart, Demayo, Francesco, Hussell, Tracy, Worthen, G Scott, Ray, David, Loudon, Andrew
Format: Artigo
Language:Inglês
Published: 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268501/
https://ncbi.nlm.nih.gov/pubmed/25064128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3599
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