Circadian variation in pulmonary inflammatory responses is independent of rhythmic glucocorticoid signaling in airway epithelial cells

The circadian clock is a critical regulator of immune function. We recently highlighted a role for the circadian clock in a mouse model of pulmonary inflammation. The epithelial clock protein Bmal1 was required to regulate neutrophil recruitment in response to inflammatory challenge. Bmal1 regulated...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Ince, Louise M., Zhang, Zhenguang, Beesley, Stephen, Vonslow, Ryan M., Saer, Ben R., Matthews, Laura C., Begley, Nicola, Gibbs, Julie E., Ray, David W., Loudon, Andrew S. I.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2019
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Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355062/
https://ncbi.nlm.nih.gov/pubmed/29965797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201800026RR
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