טוען...
Glutamine oxidation maintains the TCA cycle and cell survival during impaired mitochondrial pyruvate transport
Alternative modes of metabolism enable cells to resist metabolic stress. Inhibiting these compensatory pathways may produce synthetic lethality. We previously demonstrated that glucose deprivation stimulated a pathway in which acetyl-CoA was formed from glutamine downstream of glutamate dehydrogenas...
שמור ב:
| הוצא לאור ב: | Mol Cell |
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| Main Authors: | , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2014
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4268166/ https://ncbi.nlm.nih.gov/pubmed/25458842 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.09.025 |
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