Cbl-family ubiquitin ligases and their recruitment of CIN85 are largely dispensable for epidermal growth factor receptor endocytosis

Members of the Casitas B-Lineage Lymphoma (Cbl) family (Cbl, Cbl-b and Cbl-c) of ubiquitin ligases serve as negative regulators of receptor tyrosine kinases (RTKs). An essential role of Cbl-family protein-dependent ubiquitination for efficient ligand-induced lysosomal targeting and degradation is no...

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Gepubliceerd in:Int J Biochem Cell Biol
Hoofdauteurs: Ahmad, Gulzar, Mohapatra, Bhopal, Schulte, Nancy A., Nadeau, Scott, Luan, Haitao, Zutshi, Neha, Tom, Eric, Ortega-Cava, Cesar, Tu, Chun, Sanada, Masashi, Ogawa, Seishi, Toews, Myron L., Band, Vimla, Band, Hamid
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268055/
https://ncbi.nlm.nih.gov/pubmed/25449262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2014.10.019
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