USP11 regulates p53 stability by deubiquitinating p53

The p53 tumor suppressor protein coordinates the cellular responses to a broad range of cellular stresses, leading to DNA repair, cell cycle arrest or apoptosis. The stability of p53 is essential for its tumor suppressor function, which is tightly controlled by ubiquitin-dependent degradation primar...

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Bibliografiske detaljer
Udgivet i:J Zhejiang Univ Sci B
Main Authors: Ke, Jia-ying, Dai, Cong-jie, Wu, Wen-lin, Gao, Jin-hua, Xia, Ai-juan, Liu, Guang-ping, Lv, Kao-sheng, Wu, Chun-lin
Format: Artigo
Sprog:Inglês
Udgivet: Zhejiang University Press 2014
Fag:
Biomedicine & Biotechnology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4265557/
https://ncbi.nlm.nih.gov/pubmed/25471832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1631/jzus.B1400180
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