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USP11 regulates p53 stability by deubiquitinating p53
The p53 tumor suppressor protein coordinates the cellular responses to a broad range of cellular stresses, leading to DNA repair, cell cycle arrest or apoptosis. The stability of p53 is essential for its tumor suppressor function, which is tightly controlled by ubiquitin-dependent degradation primar...
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| Publicado no: | J Zhejiang Univ Sci B |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Zhejiang University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4265557/ https://ncbi.nlm.nih.gov/pubmed/25471832 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1631/jzus.B1400180 |
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