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USP4 inhibits p53 through deubiquitinating and stabilizing ARF-BP1
Tumour suppressor p53 levels in the cell are tightly regulated by controlled degradation through ubiquitin ligases including Mdm2, COP1, Pirh2, and ARF-BP1. The ubiquitination process is reversible via deubiquitinating enzymes, such as ubiquitin-specific peptidases (USPs). In this study, we identifi...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3117646/ https://ncbi.nlm.nih.gov/pubmed/21522127 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.125 |
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