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Protein phosphatase 1 inhibits p53 signaling by dephosphorylating and stabilizing Mdmx
The activation and stabilization of the p53 protein play a major role in the DNA damage response. Protein levels of p53 are tightly controlled by transcriptional regulation and a number of positive and negative posttranslational modifiers, including kinases, phosphatases, E3 ubiquitin ligases, deubi...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3595384/ https://ncbi.nlm.nih.gov/pubmed/23277204 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2012.12.014 |
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