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USP4 inhibits p53 and NF-κB through deubiquitinating and stabilizing HDAC2

Histone deacetylases (HDACs) are major epigenetic modulators involved in a broad spectrum of human diseases including cancers. As HDACs are promising targets of cancer therapy, it is important to understand the mechanisms of HDAC regulation. In this study, we show that ubiquitin-specific peptidase 4...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Oncogene
Päätekijät: Li, Z, Hao, Q, Luo, J, Xiong, J, Zhang, S, Wang, T, Bai, L, Wang, W, Chen, M, Gu, L, Lv, K, Chen, J
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4895393/
https://ncbi.nlm.nih.gov/pubmed/26411366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.349
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