Initial Testing (Stage 1) of Eribulin, a Novel Tubulin Binding Agent, by the Pediatric Preclinical Testing Program

BACKGROUND: Antimitotic agents are essential components for curative therapy of pediatric acute leukemias and many solid tumors. Eribulin is a novel agent that differs from both Vinca alkaloids and taxanes in its mode of binding to tubulin polymers. PROCEDURES: Eribulin was tested against the PPTP i...

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Publicado no:Pediatr Blood Cancer
Main Authors: Kolb, E. Anders, Gorlick, Richard, Reynolds, C. Patrick, Kang, Min H., Carol, Hernan, Lock, Richard, Keir, Stephen T., Maris, John M., Billups, Catherine A., DesJardins, Christopher, Kurmasheva, Raushan T., Houghton, Peter J., Smith, Malcolm A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4263960/
https://ncbi.nlm.nih.gov/pubmed/23553917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.24517
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