Heme-binding-mediated negative regulation of the tryptophan metabolic enzyme indoleamine 2,3-dioxygenase 1 (IDO1) by IDO2

Indoleamine 2,3-dioxygenases (IDOs) are tryptophan-catabolizing enzymes with immunomodulatory functions. However, the biological role of IDO2 and its relationship with IDO1 are unknown. To assess the relationship between IDO2 and IDO1, we investigated the effects of co-expression of human (h) IDO2 o...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Exp Mol Med
Päätekijät: Lee, Young-Kwan, Lee, Hoon Bok, Shin, Dong-Mi, Kang, Min Jueng, Yi, Eugene C, Noh, Seungjoo, Lee, Jaewoo, Lee, Chulbom, Min, Chang-Ki, Choi, Eun Young
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2014
Aiheet:
Original Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4261913/
https://ncbi.nlm.nih.gov/pubmed/25394548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2014.69
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