Transcriptional regulation of indoleamine 2,3-dioxygenase (IDO) by tryptophan and its analogue: Down-regulation of the indoleamine 2,3-dioxygenase (IDO) transcription by tryptophan and its analogue

Indoleamine 2,3-dioxygenase (IDO; EC 1.13.11.42) is a rate-limiting enzyme involved in the catabolism of tryptophan, which is an essential amino acid. It is induced under pathological conditions, such as the presence of viral infections or tumour cells. This enzyme is induced by IFN-γ in the mouse r...

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Detalhes bibliográficos
Main Authors: Okamoto, Takeaki, Toné, Shigenobu, Kanouchi, Hiroaki, Miyawaki, Chie, Ono, Sayuri, Minatogawa, Yohsuke
Formato: Artigo
Idioma:Inglês
Publicado em: Kluwer Academic Publishers 2007
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267499/
https://ncbi.nlm.nih.gov/pubmed/19003025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-007-9081-4
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