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Angiotensin II Stimulates Protein Kinase D–Dependent Histone Deacetylase 5 Phosphorylation and Nuclear Export Leading to Vascular Smooth Muscle Cell Hypertrophy

BACKGROUND: Angiotensin II (Ang II) induces the phenotypic modulation and hypertrophy of vascular smooth muscle cells (VSMCs), which is implicated in the pathogenesis of hypertension, atherosclerosis, and diabetes. In this study, we tested the hypothesis that histone deacetylases 5 (HDAC5) and its s...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Arterioscler Thromb Vasc Biol
Prif Awduron: Xu, Xiangbin, Ha, Chang-Hoon, Wong, Chelsea, Wang, Weiye, Hausser, Angelika, Pfizenmaier, Klaus, Olson, Eric N., McKinsey, Timothy A., Jin, Zheng-Gen
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4259271/
https://ncbi.nlm.nih.gov/pubmed/17823368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.107.151704
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