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Angiotensin II Stimulates Protein Kinase D–Dependent Histone Deacetylase 5 Phosphorylation and Nuclear Export Leading to Vascular Smooth Muscle Cell Hypertrophy

BACKGROUND: Angiotensin II (Ang II) induces the phenotypic modulation and hypertrophy of vascular smooth muscle cells (VSMCs), which is implicated in the pathogenesis of hypertension, atherosclerosis, and diabetes. In this study, we tested the hypothesis that histone deacetylases 5 (HDAC5) and its s...

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發表在:Arterioscler Thromb Vasc Biol
Main Authors: Xu, Xiangbin, Ha, Chang-Hoon, Wong, Chelsea, Wang, Weiye, Hausser, Angelika, Pfizenmaier, Klaus, Olson, Eric N., McKinsey, Timothy A., Jin, Zheng-Gen
格式: Artigo
語言:Inglês
出版: 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4259271/
https://ncbi.nlm.nih.gov/pubmed/17823368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.107.151704
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