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Splenectomy Promotes Indirect Elimination of Intraocular Tumors by CD8(+) T cells That Is Associated with IFNγ and Fas/FasL-dependent Activation of Intratumoral Macrophages
Ocular immune privilege (IP) limits immune surveillance of intraocular tumors as certain immunogenic tumor cell lines (P815, E.G7-OVA) that are rejected when transplanted in the skin grow progressively when placed in the anterior chamber (a.c.) of the eye. As splenectomy (SPLNX) is known to terminat...
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| 發表在: | Cancer Immunol Res |
|---|---|
| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4258428/ https://ncbi.nlm.nih.gov/pubmed/25248763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-14-0093-T |
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