Splenectomy Promotes Indirect Elimination of Intraocular Tumors by CD8(+) T cells That Is Associated with IFNγ and Fas/FasL-dependent Activation of Intratumoral Macrophages

Ocular immune privilege (IP) limits immune surveillance of intraocular tumors as certain immunogenic tumor cell lines (P815, E.G7-OVA) that are rejected when transplanted in the skin grow progressively when placed in the anterior chamber (a.c.) of the eye. As splenectomy (SPLNX) is known to terminat...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cancer Immunol Res
Prif Awduron: Miller, Maxine R., Mandell, Jonathan B., Beatty, Kelly M., Harvey, Stephen A. K., Rizzo, Michael J., Previte, Dana M., Thorne, Stephen H., McKenna, Kyle C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4258428/
https://ncbi.nlm.nih.gov/pubmed/25248763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-14-0093-T
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