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Splenectomy Promotes Indirect Elimination of Intraocular Tumors by CD8(+) T cells That Is Associated with IFNγ and Fas/FasL-dependent Activation of Intratumoral Macrophages
Ocular immune privilege (IP) limits immune surveillance of intraocular tumors as certain immunogenic tumor cell lines (P815, E.G7-OVA) that are rejected when transplanted in the skin grow progressively when placed in the anterior chamber (a.c.) of the eye. As splenectomy (SPLNX) is known to terminat...
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| Publicat a: | Cancer Immunol Res |
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| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4258428/ https://ncbi.nlm.nih.gov/pubmed/25248763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-14-0093-T |
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