Oligomer Formation of Tau Protein Hyperphosphorylated in Cells

Abnormal phosphorylation (“hyperphosphorylation”) and aggregation of Tau protein are hallmarks of Alzheimer disease and other tauopathies, but their causative connection is still a matter of debate. Tau with Alzheimer-like phosphorylation is also present in hibernating animals, mitosis, or during em...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Tepper, Katharina, Biernat, Jacek, Kumar, Satish, Wegmann, Susanne, Timm, Thomas, Hübschmann, Sabrina, Redecke, Lars, Mandelkow, Eva-Maria, Müller, Daniel J., Mandelkow, Eckhard
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2014
Soggetti:
Protein Structure and Folding
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256367/
https://ncbi.nlm.nih.gov/pubmed/25339173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.611368
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