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In Vivo Occupancy of Mitochondrial Single-Stranded DNA Binding Protein Supports the Strand Displacement Mode of DNA Replication

Mitochondrial DNA (mtDNA) encodes for proteins required for oxidative phosphorylation, and mutations affecting the genome have been linked to a number of diseases as well as the natural ageing process in mammals. Human mtDNA is replicated by a molecular machinery that is distinct from the nuclear re...

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Publicat a:PLoS Genet
Autors principals: Miralles Fusté, Javier, Shi, Yonghong, Wanrooij, Sjoerd, Zhu, Xuefeng, Jemt, Elisabeth, Persson, Örjan, Sabouri, Nasim, Gustafsson, Claes M., Falkenberg, Maria
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256270/
https://ncbi.nlm.nih.gov/pubmed/25474639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004832
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