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Human mitochondrial RNA polymerase primes lagging-strand DNA synthesis in vitro
The mitochondrial transcription machinery synthesizes the RNA primers required for initiation of leading-strand DNA synthesis in mammalian mitochondria. RNA primers are also required for initiation of lagging-strand DNA synthesis, but the responsible enzyme has so far remained elusive. Here, we pres...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2516254/ https://ncbi.nlm.nih.gov/pubmed/18685103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805399105 |
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