Human mitochondrial RNA polymerase primes lagging-strand DNA synthesis in vitro

The mitochondrial transcription machinery synthesizes the RNA primers required for initiation of leading-strand DNA synthesis in mammalian mitochondria. RNA primers are also required for initiation of lagging-strand DNA synthesis, but the responsible enzyme has so far remained elusive. Here, we pres...

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Bibliografiske detaljer
Main Authors: Wanrooij, Sjoerd, Fusté, Javier Miralles, Farge, Géraldine, Shi, Yonghong, Gustafsson, Claes M., Falkenberg, Maria
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2008
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2516254/
https://ncbi.nlm.nih.gov/pubmed/18685103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805399105
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