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In vivo mutagenesis reveals that OriL is essential for mitochondrial DNA replication
The mechanisms of mitochondrial DNA replication have been hotly debated for a decade. The strand-displacement model states that lagging-strand DNA synthesis is initiated from the origin of light-strand DNA replication (OriL), whereas the strand-coupled model implies that OriL is dispensable. Mammali...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
European Molecular Biology Organization
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3513414/ https://ncbi.nlm.nih.gov/pubmed/23090476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2012.161 |
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