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Desferrithiocin: A Search for Clinically Effective Iron Chelators

[Image: see text] The successful search for orally active iron chelators to treat transfusional iron-overload diseases, e.g., thalassemia, is overviewed. The critical role of iron in nature as a redox engine is first described, as well as how primitive life forms and humans manage the metal. The pro...

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Bibliografiset tiedot
Julkaisussa:J Med Chem
Päätekijät: Bergeron, Raymond J., Wiegand, Jan, McManis, James S., Bharti, Neelam
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Chemical Society 2014
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4255733/
https://ncbi.nlm.nih.gov/pubmed/25207964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm500828f
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