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Desferrithiocin: A Search for Clinically Effective Iron Chelators
[Image: see text] The successful search for orally active iron chelators to treat transfusional iron-overload diseases, e.g., thalassemia, is overviewed. The critical role of iron in nature as a redox engine is first described, as well as how primitive life forms and humans manage the metal. The pro...
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| Veröffentlicht in: | J Med Chem |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Chemical
Society
2014
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4255733/ https://ncbi.nlm.nih.gov/pubmed/25207964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm500828f |
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