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The Design, Synthesis, and Evaluation of Organ-Specific Iron Chelators
A series of iron chelators, three (S)-4,5-dihydro-2-(2-hydroxyphenyl)-4-methyl-4-thiazolecarboxylic acid (DADFT) and three (S)-4,5-dihydro-2-(2-hydroxyphenyl)-4-thiazolecarboxylic acid (DADMDFT) analogues are synthesized and assessed for their lipophilicity (log P(app)), iron-clearing efficiency (IC...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2006
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2516204/ https://ncbi.nlm.nih.gov/pubmed/17125256 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm0608816 |
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