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Desferrithiocin Analogues and Nephrotoxicity
The syntheses of a series of 4′-O-alkylated (S)-4,5-dihydro-2-(2,4-dihydroxyphenyl)-4-methyl-4-thiazolecarboxylic acid and 5′-O-alkylated (S)-4,5-dihydro-2-(2,5-dihydroxyphenyl)-4-methyl-4-thiazolecarboxylic acid ligands are described. Their partition between octanol and water, logP(app), is determi...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2778308/ https://ncbi.nlm.nih.gov/pubmed/18788724 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm8003398 |
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