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Desferrithiocin Analogues and Nephrotoxicity

The syntheses of a series of 4′-O-alkylated (S)-4,5-dihydro-2-(2,4-dihydroxyphenyl)-4-methyl-4-thiazolecarboxylic acid and 5′-O-alkylated (S)-4,5-dihydro-2-(2,5-dihydroxyphenyl)-4-methyl-4-thiazolecarboxylic acid ligands are described. Their partition between octanol and water, logP(app), is determi...

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Hlavní autoři: Bergeron, Raymond J., Wiegand, Jan, McManis, James S., Bharti, Neelam, Singh, Shailendra
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2778308/
https://ncbi.nlm.nih.gov/pubmed/18788724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm8003398
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