Lanean...

The Impact of Polyether Chain Length on the Iron Clearing Efficiency and Physiochemical Properties of Desferrithiocin Analogues

(S)-2-(2,4-Dihydroxyphenyl)-4,5-dihydro-4-methyl-4-thiazolecarboxylic acid (2) was abandoned in clinical trials as an iron chelator for the treatment of iron overload disease because of its nephrotoxicity. However, subsequent investigations revealed that replacing the 4′-(HO) of 2 with a 3,6,9-triox...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Bergeron, Raymond J., Bharti, Neelam, Wiegand, Jan, McManis, James S., Singh, Shailendra, Abboud, Khalil A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951135/
https://ncbi.nlm.nih.gov/pubmed/20232803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm9018146
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!