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SGK3 mediates INPP4B-dependent PI 3-Kinase signaling in breast cancer
Oncogenic mutations in PIK3CA, the gene encoding the catalytic subunit of phosphoinositide 3-kinase (PI 3-K), occur with high frequency in breast cancer. The protein kinase Akt is considered to be the primary effector of PIK3CA, although mechanisms by which PI 3-K mediates Akt-independent tumorigeni...
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| Vydáno v: | Mol Cell |
|---|---|
| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4255362/ https://ncbi.nlm.nih.gov/pubmed/25458846 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.09.023 |
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