SGK3 mediates INPP4B-dependent PI 3-Kinase signaling in breast cancer

Oncogenic mutations in PIK3CA, the gene encoding the catalytic subunit of phosphoinositide 3-kinase (PI 3-K), occur with high frequency in breast cancer. The protein kinase Akt is considered to be the primary effector of PIK3CA, although mechanisms by which PI 3-K mediates Akt-independent tumorigeni...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Cell
Main Authors: Gasser, Jessica A., Inuzuka, Hiroyuki, Lau, Alan W., Wei, Wenyi, Beroukhim, Rameen, Toker, Alex
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4255362/
https://ncbi.nlm.nih.gov/pubmed/25458846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.09.023
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki