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TACE Activation by MAPK-Mediated Regulation of Cell Surface Dimerization and TIMP3 Association
Ectodomain shedding mediated by tumor necrosis factor–α (TNF-α)–converting enzyme [TACE; also known as ADAM17 (a disintegrin and metalloproteinase 17)] provides an important switch in regulating cell proliferation, inflammation, and cancer progression. TACE-mediated ectodomain cleavage is activated...
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| 出版年: | Sci Signal |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4254802/ https://ncbi.nlm.nih.gov/pubmed/22550340 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2002689 |
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