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Smad2 Is Essential for Maintenance of the Human and Mouse Primed Pluripotent Stem Cell State
Human embryonic stem cells and mouse epiblast stem cells represent a primed pluripotent stem cell state that requires TGF-β/activin signaling. TGF-β and/or activin are commonly thought to regulate transcription through both Smad2 and Smad3. However, the different contributions of these two Smads to...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3689995/ https://ncbi.nlm.nih.gov/pubmed/23649632 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.446591 |
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