Arginine methylation of SMAD7 by PRMT1 in TGF-β–induced epithelial–mesenchymal transition and epithelial stem-cell generation

The epithelial-to-mesenchymal transdifferentiation (EMT) is crucial for tissue differentiation in development and drives essential steps in cancer and fibrosis. EMT is accompanied by reprogramming of gene expression and has been associated with the epithelial stem-cell state in normal and carcinoma...

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Bibliografische gegevens
Gepubliceerd in:J Biol Chem
Hoofdauteurs: Katsuno, Yoko, Qin, Jian, Oses-Prieto, Juan, Wang, Hongjun, Jackson-Weaver, Olan, Zhang, Tingwei, Lamouille, Samy, Wu, Jian, Burlingame, Alma, Xu, Jian, Derynck, Rik
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2018
Onderwerpen:
Signal Transduction
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6109915/
https://ncbi.nlm.nih.gov/pubmed/29907569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002027
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