Emergence of the Phosphoinositide 3-Kinase-Akt-Mammalian Target of Rapamycin Axis in Transforming Growth Factor-β-Induced Epithelial-Mesenchymal Transition

During development and in pathological contexts such as fibrosis and cancer progression, epithelial cells can initiate a complex transcriptional reprogramming, accompanied by dramatic morphological changes, in a process named ‘epithelial-mesenchymal transition’ (EMT). In this transition, epithelial...

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Bibliographic Details
Main Authors: Lamouille, Samy, Derynck, Rik
Format: Artigo
Language:Inglês
Published: S. Karger AG 2010
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3030503/
https://ncbi.nlm.nih.gov/pubmed/21041997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000320172
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