Arginine methylation initiates BMP-induced Smad signaling

Kinase activation and substrate phosphorylation commonly form the backbone of signaling cascades. Bone morphogenetic proteins (BMPs), a subclass of TGF-β family ligands, induce activation of their signaling effectors, the Smads, through C-terminal phosphorylation by transmembrane receptor kinases. H...

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Main Authors: Xu, Jian, Wang, A. Hongjun, Oses-Prieto, Juan, Makhijani, Kalpana, Katsuno, Yoko, Pei, Ming, Yan, Leilei, Zheng, Y. George, Burlingame, Alma, Brückner, Katja, Derynck, Rik
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3951972/
https://ncbi.nlm.nih.gov/pubmed/23747011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.05.004
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